POTASSIUM METHOXYCINNAMATE
Potassium 4-methoxysalicylate
CAS: 152312-71-5
Molecular Formula: C8H7KO4
POTASSIUM METHOXYCINNAMATE - Names and Identifiers
| Name | Potassium 4-methoxysalicylate |
| Synonyms | MSAK 4MSK 4-MSAK 4MS KTranexamic Acid POTASSIUM METHOXYCINNAMATE Potassium methoxysalicylate Potassium 4-methoxysalicylate POTASSIUM 4-METHOXYSALICYLATE Potassium 2-hydroxy-4-methoxybenzoate P-Methoxy salicylic acid potassium salt Potassium methoxysalicylate Potassium 2-Hydroxy-4-methoxybenzoate |
| CAS | 152312-71-5 |
| InChI | InChI=1/C8H8O4.K/c1-12-5-2-3-6(8(10)11)7(9)4-5;/h2-4,9H,1H3,(H,10,11);/q;+1/p-1 |
POTASSIUM METHOXYCINNAMATE - Physico-chemical Properties
| Molecular Formula | C8H7KO4 |
| Molar Mass | 206.24 |
| Melting Point | >220°C (dec.) |
| Solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
| Appearance | Almost white crystal or powder |
| Color | White to Off-White |
| Storage Condition | Inert atmosphere,Room Temperature |
POTASSIUM METHOXYCINNAMATE - Reference Information
| synthesis | (1) will 2,4? Dihydroxybenzoic acid is slowly added into sodium hydroxide alkaline aqueous solution, and the temperature is controlled below 30 ℃, when 2,4? After all dihydroxybenzoic acid is added and dissolved, the temperature is lowered to 20 ℃, dimethyl sulfate is slowly added dropwise, the temperature is controlled below 40 ℃, after the dropwise is completed, the temperature is kept at 30~40 ℃ for 6 hours, after the reaction is over, the temperature is raised to 60 ℃, stirred for 30 minutes, the unreacted dimethyl sulfate is completely decomposed, then the temperature is lowered to normal temperature, the PH is adjusted to 1 with 10% hydrochloric acid, and a large amount of white solid substances are precipitated, centrifuge, rinse with deionized water, dry, get 4? Methoxysalicylic acid crude; (2) 4? The crude methoxysalicylic acid is added to deionized water, heated to 80 ℃, stirred for 0.5 hours, filtered while hot, dried to obtain 4? Pure methoxysalicylic acid; (3) in the deionized aqueous solution of potassium carbonate, raise the temperature to 50 ℃, slowly add 4? Methoxysalicylic acid, adjust PH = 7, stop adding 4? Methoxysalicylic acid, stirring for 30 minutes, starting to recover solvent, cooling crystallization, suction filtration, 4? Crude potassium methoxysalicylate; (4) will 4? The crude potassium methoxysalicylate is dissolved in 50% ethanol solution, the activated carbon is decolorized for 40 minutes, suction filtration, cooling crystallization, vacuum drying, and 4? Pure methoxy potassium salicylate. |
| effect | potassium 4-methoxysalicylate (potassium 4-methoxysalicylate) has a structure similar to salicylic acid. it is a new type of medicinal whitening ingredient, which is used in cosmetics and plays a whitening role. it is an effective ingredient of cosmetics. Potassium 4-methoxysalicylate can coordinate cutin metabolism, correct abnormal epidermal hyperplasia, promote the discharge of melanin, achieve skin smoothness and whitening; it can also block the source of melanin production and improve self-healing. It can be used in conjunction with various types of whitening products to improve the whitening effect and has good development prospects. |
Last Update：2024-04-09 21:01:54
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